生物分子化学研究室 - 北海道大学大学院工学研究院・工学部・総合化学院

D3久語の論文がPolymer Journal に掲載されました (IF=2.8)。希アルカリ後処理を複数回行うことで、セルロースⅡ型の結晶化度を20％程度向上させることに成功しました。この方法を用いることにより、高結晶性のセルロースII 型を調製することが可能となり、高い機械的強度を有するセルロースII 型材料の開発につながることが期待されます https://www.nature.com/articles/s41428-024-00890-0.

高分子化学研究室との共同研究の成果が水上くんを 筆答著者として、ACS Macro Letters に掲載されました (IF=5.8)。再生可能な資源として大量に存在するセルロースから誘導されるモノマーを用い、開環重合を行うことによって様々な構造の多糖を合成可能です。また、解重合することによってケミカルリサイクルが可能であり、サーキュラーエコノミーへの貢献が期待されます。 https://doi.org/10.1021/acsmacrolett.3c00720.

D3久語の論文がCarbohydrate Polymers に掲載されました (IF=11.2)。低温希アルカリ処理におけるセルロースI 型からII 型への結晶転移機構を明らかにすることに成功しました。また、低温希アルカリ処理の処理条件を調整することで、結晶転移を制御できることが示唆され、この方法を用いることによるセルロースI 型およびII 型からなる新規セルロース材料の創製が期待されます。 https://doi.org/10.1016/j.carbpol.2024.121907.

Chaehun (D2) の研究成果が GIANT に掲載されました (IF=7)。 高分子化学研究室との共同研究の成果です。 様々な分子パラメータを有するバイオベースの糖鎖―テルペノイド複合材料を用いて三次元ネットワーク構造であるジャイロイドや穴あきラメラ構造の構築に成功しました。 特に、バルクおよび薄膜でも安定的に三次元ネットワーク構造を構築したことで本材料がナノテンプレートの製造に応用が期待されます。 https://doi.org/10.1016/j.giant.2023.100211.

高分子化学研究室との共同研究の成果が江部くんを筆頭著者として Angewandte Chemie に掲載されました。 本報告ではロタキサンの形で多環状高分子を取り込んだネットワークポリマーの合成に成功し、この巨大なロタキサンを 「マクロロタキサン」と名付けました。マクロロタキサンは環状高分子のリングの数や大きさを自在にアレンジ できるため構造や分子設計に非常に大きな自由度があり、今後幅広い用途への応用が期待されます。 https://doi.org/10.1002/anie.202304493.

高分子化学研究室との共同研究の成果が海老井くんを筆答著者として、Polymer Chemistry に掲載されました(IF=5.364)。 環化重合により多環状ポリスチレンの系統的な合成に成功し、多環状構造が諸物性に与える影響を系統的に評価しました。 さらにポリスチレンセグメントを有する多環状コポリマーの合成にも成功しました。 https://pubs.rsc.org/en/content/articlelanding/2023/py/d3py00449j.

高分子化学研究室、東京大学五十嵐先生、砂川先生との共同研究の成果が勝原くんを 筆答著者として、Carbohydrate Polymers に掲載されました (IF=10.723)。様々な 置換度のアセチルセルロースとポリデカノラクトンとのトリブロックコポリマー (AcCelx-b-PDL-b-AcCelx) における構造、物性を評価しました。セルロースを含む新 たな熱可塑性エラストマーとしての利用が期待されます。 https://www.sciencedirect.com/science/article/pii/S0144861723004411?via%3Dih.

高分子化学研究室との共同研究の成果が、磯野先生を筆頭著者として Biomacromolecules（IF= 6.978）に掲載されました。国立清華大学のChen先生と CERMAVのBorsali先生との国際共著でもあります。 マルトオリゴ糖とソラネソー ルからなる単分散ブロックコオリゴマーのミクロ相分離により、糖質ミクロドメ インを有する様々なナノスケールのモルフォロジーを構築することに成功しまし た。従来のLAM、HEX、BCCだけでなく、GYR、HPL、Fdddネットワーク形態を持つ ナノ材料へのアクセスが可能になりました。 "Tailored Solid-State Carbohydrate Nanostructures Based on Star-Shaped Discrete Block Co-Oligomers" https://pubs.acs.org/doi/10.1021/acs.biomac.2c00813.

高分子化学研究室との共同研究の成果が Polymer Chemistry に掲載されました( IF=5.364)。 ピバリン酸セシウムを触媒とした、エポキシドと無水トリメリット 酸の開環交互共重合によるハイパーブランチポリエステル(HBPE)の新規合成法を 開発しました。無水物、エポキシドおよびアルコール開始剤を適切に選択するこ とで、異なる骨格構造を持つ様々なHBPEを得ることができます。その汎用性と簡 便性より添加剤やバイオメディカルなど幅広い用途で利用できる可能性がありま す。 "Synthesis of Hyperbranched Polyester via Ring-opening Alternating Copolymerisation of Epoxide with Cyclic Anhydride having a Carboxyl Group" https://pubs.rsc.org/en/Content/ArticleLanding/2022/PY/D2PY00571A.

高分子化学研究室との共同研究の成果がMacromolecules に掲載されました (IF= 6.057)。 アルカリ金属カルボン酸塩がエポキシドおよびエピスルフィドの開環 重合にシンプルかつ効率的な触媒として使用でき，コントロール可能な分子量お よび低分散性を有するポリエーテルおよびポリチオエーテルを得ることができる ことを実証しました。 "Polyether/Polythioether Synthesis via Ring-Opening Polymerization of Epoxides and Episulfides Catalyzed by Alkali Metal Carboxylates" https://pubs.acs.org/doi/10.1021/acs.macromol.2c00656.

分子集積化学研究室の山本先生との共同研究の成果が Polymers に掲載されまし た (IF=4.967)。環状ポリマーが直鎖状ポリマーに比べてAgNPsに優れた安定性を 付与していることを明確にしました。また、環状ポリエチレングリコールの使用 によりコロイド安定性が向上したことで、高い耐塩性を利用した生体系への応用 が可能になりました。 "Size Control and Enhanced Stability of Silver Nanoparticles by Cyclic Poly(Ethylene Glycol)" https://www.mdpi.com/2073-4360/14/21/4535.

分子集積化学研究室の山本先生との共同研究の成果が Polymers に掲載されまし た (IF=4.967)。重合度が14から43の環状ポリ(3-ヘキシルチオフェン)を合成し， その環状トポロジーに起因する酸化還元挙動を調査しました。 "Molecular Weight-Dependent Oxidation and Optoelectronic Properties of Defect-Free Macrocyclic Poly(3-hexylthiophene)" https://www.mdpi.com/2073-4360/15/3/666.

苫小牧高専甲野先生との共同研究の成果が ACS Applied Nano Materials に掲載 されました (IF=6.140)。4級アンモニウム塩のNFBCへの導入によるカチオン化に より、抗菌性材料、ナノフィラー、凝集剤としての利用が可能となりました。 https://doi.org/10.1021/acsanm.3c00616.

Taiki Nishimura, Satoshi Katsuhara, Chaehun Lee, Brian J. Ree, Redouane Borsali, Takuya Yamamoto, Kenji Tajima, Toshifumi Satoh, and Takuya Isono, Fabrication of Ultrafine, Highly Ordered Nanostructures Using Carbohydrate-Inorganic Hybrid Block Copolymers, Nanomaterials 2022, 12, 1653, DOI: 10.3390/nano12101653.

Hamidah binti Hashim, Nur Aisyah Adlin binti Emran, Takuya Isono, Satoshi Katsuhara, Hiroko Ninoyu, Tokuo Matsushima, Takuya Yamamoto, Redouane Borsali, Toshifumi Satoh, Kenji Tajima, Improving the mechanical properties of polycaprolactone using functionalized nanofibrillated bacterial cellulose with high dispersibility and long fiber length as a reinforcement material, Composites Part A 2022, 158, 106978, DOI: 10.1016/j.compositesa.2022.106978.

Tomohisa Watanabe, Yubo Wang, Tomoko Ono, Satoru Chimura, Takuya Isono, Kenji Tajima, Toshifumi Satoh, Shin-ichiro Sato, Daichi Ida and Takuya Yamamoto, Topology and Sequence-Dependent Micellization and Phase Separation of Pluronic L35, L64, 10R5, and 17R4: Effects of Cyclization and the Chain Ends, Polymer, 2022, 14, 1823, DOI: 10.3390/polym14091823.

Ryo Takahama, Honami Kato, Go Takayama, Kenji Tajima and Tetsuo Kondo, Physical characteristics and cell-adhesive properties of in vivo fabricated bacterial cellulose/hyaluronan nanocomposites, Cellulose, 2022, DOI: 10.1007/s10570-022-04480-2.

Satoshi Katsuhara, Yasuko Takagi, Naoki Sunagawa, Kiyohiko Igarashi, Takuya Yamamoto, Kenji Tajima, Takuya Isono, and Toshifumi Satoh, セロオリゴ糖誘導体をハードセグメントとするバイオベースエラストマーの開発, Cellulose Commun., 2021, 28, 140-148.

Takaaki Fujiwara, Ayumi Fujishima, Yui Nakamura, Kenji Tajima, and Min Yao, Structural snapshot of a glycoside hydrolase family 8 endo-β-1,4-glucanase capturing the state after cleavage of the scissile bond, Acta Cryst. 2022, D78, 228-237, DOI: doi.org/10.1107/s2059798321012882.

Hiroyuki Kono, Haruto Tsujisaki, and Kenji Tajima, Reinforcing Poly(methyl methacrylate) with Bacterial Cellulose Nanofibers Chemically Modified with Methacryolyl Groups, Nanomaterials, 2022, 12, 537, DOI: doi.org/10.3390/nano12030537.

Onyinyechukwu Justina Oziri, Masatoshi Maeki, Manabu Tokeshi, Takuya Isono, Kenji Tajima, Toshifumi Satoh, Shin-ichiro Sato, Takuya Yamamoto, Topology-Dependent Interaction of Cyclic Poly(ethylene glycol) Complexed with Gold Nanoparticles against Bovine Serum Albumin for a Colorimetric Change, Langmuir 2021, ASAP, DOI: doi.org/10.1021/acs.langmuir.1c03027.

Hiroyuki Kono, Eiki Tsukamoto, Kenji Tajima, Facile Post-Carboxymethylation of Cellulose Nanofiber Surfaces for Enhanced Water Dispersibility, ACS Omega 2021, 6, 34107-34114, DOI: doi.org/10.1021/acsomega.1c05603.

Saburo Kobayashi, Mayoh Ashiya, Takuya Yamamoto, Kenji Tajima, Yasunori Yamamoto, Takuya Isono, Toshifumi Satoh, Suzuki–Miyaura Catalyst-Transfer Polycondensation of Triolborate-Type Carbazole Monomers, Polymers, 2021, 13, 4168, DOI: doi.org/10.3390/polym13234168.

Oziri Onyinyechukwu J., Yubo Wang, Tomohisa Watanabe, Shuya Uno, Masatoshi Maeki, Manabu Tokeshi, Takuya Isono, Kenji Tajima, Toshifumi Satoh, Shin-ichiro, Sato, Yutaka Miura, and Takuya Yamamoto, PEGylation of Silver Nanoparticles by Physisorption of Cyclic Poly(Ethylene Glycol) for Enhanced Dispersion Stability, Antimicrobial Activity, and Cytotoxicity, Nanoscale Adv., 2022, 4, 532-545, DOI: 10.1039/D1NA00720C.

Ryo Takahama, Honami Kato, Kenji Tajima, Satomi Tagawa, and Tetsuo Kondo, Biofabrication of a Hyaluronan/Bacterial Cellulose Composite Nanofibril by Secretion from Engineered Gluconacetobacter, Biomacromolecules, 2021, 22, 4709-4719, DOI: 10.1021/acs.biomac.1c00987.

Kenji Tajima, Tomoya Imai, Toshifumi Yui, Min Yao, Inder Saxena, Cellulose-synthesizing machinery in bacteria, Cellulose, 2021, DOI: 10.1007/s10570-021-04225-7.

Yoshinobu Mato, Maho Sudo, Hironori Marubayashi, Takuya Yamamoto, Kenji Tajima, Hiroshi Jinnai, Takuya Isono, Toshifumi Satoh, Densely Arrayed Cage-Shaped Polymer Topologies Synthesized via Cyclopolymerization of Star-Shaped Macromonomers, Macromolecules, 2021, 54, 9079-9090, DOI: 10.1021/acs.macromol.1c01230.

Satoshi Katsuhara, Yasuko Takagi, Naoki Sunagawa, Kiyohiko Igarashi, Takuya Yamamoto, Kenji Tajima, Takuya Isono, Toshifumi Satoh, Enhanced Self-Assembly and Mechanical Properties of Cellulose-Based Triblock Copolymers: Comparisons with Amylose-Based Triblock Copolymers, ACS Sustainable Chem. Eng., 2021, 9, 9779-9788, DOI: doi.org/10.1021/acssuschemeng.1c02180.

Hidenori Ando, Takashi Mochizuki, Amr S. Abu Lila, Shunsuke Akagi, Kenji Tajima, Kenji Fujita, Taro Shimizu, Yu Ishima, Tokuo Matsushima, Takatomo Kusano, Tatsuhiro Ishida, Doxorubicin Embedded into Nanofibrillated Bacterial Cellulose (NFBC) Produces a Promising Therapeutic Outcome for Peritoneally Metastatic Gastric Cancer in Mice Models via Intraperitoneal Direct Injection, Nanomaterials, 2021, 11, 1697, DOI: doi.org/10.3390/nano11071697.

Kodai Watanabe, Noya Kaizawa, Brian J. Ree, Takuya Yamamoto, Kenji Tajima, Takuya Isono, and Toshifumi Satoh, One-Shot Intrablock Crosslinking of Linear Diblock Copolymer to Realize Janus-shaped Single-Chain Nanoparticle, Angew. Chem. Int. Ed., 2021, 60, 2-9, DOI: 10.1002/anie.202103969.

Shunsuke Akagi, Hidenori Ando, Kenji Fujita, Taro Shimizu, Yu Ishima, Kenji Tajima, Tokuo Matsushima, Takatomo Kusano, Tatsuhiro Ishida, Therapeutic efficacy of a paclitaxel-loaded nanofibrillated bacterial cellulose (PTX/NFBC) formulation in a peritoneally disseminated gastric cancer xenograft model, International Journal of Biological Macromolecules 2021, 174, 494-501 DOI: 10.1016/j.ijbiomac.2021.01.201.

Takuya Uto, Yuki Ikeda, Naoki Sunagawa, Kenji Tajima, Min Yao, Toshifumi Yui Molecular Dynamics Simulation of Cellulose Synthase Subunit D Octamer with Cellulose Chains from Acetic Acid Bacteria: Insight into Dynamic Behaviors and Thermodynamics on Substrate Recognition, J. Chem. Theory Comput. 2021, 17, 488-496 DOI: 10.1021/acs.jctc.0c01027.

Li-Che Hsu, Takuya Isono, Yan-Cheng Lin, Saburo Kobayashi, Yun-Chi Chiang, Dai-Hua Jiang, Chih-Chien Hung, Ender Ercan, Wei-Chen Yang, Hui-Ching Hsieh, Kenji Tajima, Toshifumi Satoh, Wen-Chang Chen Stretchable OFET Memories: Tuning the Morphology and the Charge-Trapping Ability of Conjugated Block Copolymers through Soft Segment Branching, ACS Appl. Mater. Interfaces, 2021, 13, 2932-2943, DOI: 10.1021/acsami.0c18820.

Yubo Wang, Jose Enrico Q. Quinsaat, Tomoko Ono, Masatoshi Maeki, Manabu Tokeshi, Takuya Isono, Kenji Tajima, Toshifumi Satoh, Shin-ichiro Sato, Yutaka Miura, Takuya Yamamoto Enhanced dispersion stability of gold nanoparticles by the physisorption of cyclic poly(ethylene glycol), Nature Communications, 2020, 11, 6089, DOI: 10.1038/s41467-020-19947-8.

Hiroyuki Kono, Taiki Uno, Haruto Tsujisaki, Tokuo Matsushima, and Kenji Tajima Nanofibrillated Bacterial Cellulose Modified with (3-Aminopropyl)trimethoxysilane under Aqueous Conditions: Applications to Poly(methyl methacrylate) Fiber-Reinforced Nanocomposites, ACS OMEGA, 2020, 5, 29561-29569, DOI: 10.1021/acsomega.0c04533.

Saburo Kobayashi, Kaiyu Fujiwara, Dai-Hua Jiang, Takuya Yamamoto, Kenji Tajima, Yasunori Yamamoto, Takuya Isono, Toshifumi Satoh Suzuki–Miyaura Catalyst-Transfer Polycondensation of Triolborate-Type Fluorene Monomer: Toward Rapid Access to Polyfluorene-Containing Block and Graft Copolymers from Various Macroinitiators, Poly. Chem., 2020, 11, 6832-6839, DOI: 10.1039/D0PY01127D.

Takuya Isono, Ryoya Komaki, Chaehun Lee, Nao Kawakami, Brian J. Ree, Kodai Watanabe, Kohei Yoshida, Hiroaki Mamiya, Takuya Yamamoto, Redouane Borsali, Kenji Tajima, Toshifumi Satoh Rapid access to discrete and monodisperse block co-oligomers from sugar and terpenoid toward ultrasmall periodic nanostructures, Communications Chem., 2020, 3, 135, DOI: 10.1038/s42004-020-00385-y.

Kaoru Takojima, Hiroshi Makino. Tatsuya Saito, Takuya Yamamoto, Kenji Tajima, Takuya Isono, Toshifumi Satoh Organocatalytic Ring-opening Polymerization Approach to Highly Alternating Copolymers of Lactic Acid and Glycolic Acid, Poly. Chem., 2020, 11, 6365-6373, DOI: 10.1039/D0PY01082K.

Hiroyuki Kono, Taiki Uno, Haruto Tsujisaki, Hikaru Anai, Ryota Kishimoto, Tokuo Matsushima, Kenji Tajima Nanofibrillated Bacterial Cellulose Surface Modified with Methyltrimethoxysilane for Fiber-Reinforced Composites, ACS applied nano materials. 2020, 3, 8, 8232–8241, DOI: 10.1021/acsanm.0c01670.

Yoshinobu Mato, Kohei Honda, Brian J. Ree, Kenji Tajima, Takuya Yamamoto, Tetsuo Deguchi, Takuya Isono, Toshifumi Satoh Programmed folding into spiro-multicyclic polymer topologies from linear and star-shaped chains, Communications Chem. 2020, 3, 97 DOI: 10.1038/s42004-020-00355-4.

Kodai Watanabe, Satoshi Katsuhara, Hiroaki Mamiya, Yukihiko Kawamura, Takuya Yamamoto, Kenji Tajima, Takuya Isono, Toshifumi Satoh Highly Asymmetric Lamellar Nanostructures from Nanoparticle−Linear Hybrid Block Copolymers, Nanoscale 2020, 12, 16526-16534 DOI: 10.1039/D0NR05209D.

Takuya Isono, Saki Nakahira, Hui-Ching Hsieh, Satoshi Katsuhara, Hiroaki Mamiya, Takuya Yamamoto, Wen-Chang Chen, Redouane Borsali, Kenji Tajima, Toshifumi Satoh Carbohydrates as Hard Segments for Sustainable Elastomers: Carbohydrates Direct the Self-Assembly and Mechanical Properties of Fully Bio-Based Block Copolymers, Macromolecules 2020, 53, 5408-5417, DOI: 10.1021/acs.macromol.0c00611.

Muhammad Mumtaz, Yasuko Takagi, Hiroaki Mamiya, Kenji Tajima, Cécile Bouilhac, Takuya Isono, Toshifumi Satoh, Redouane Borsali Sweet Pluronic poly(propylene oxide)-b-oligosaccharide block copolymer systems: Toward sub-4 nm thin-film nanopattern resolution, European Polymer Journal 2020, 134, 109831, DOI: 10.1016/j.eurpolymj.2020.109831.

Satoshi Katsuhara, Hiroaki Mamiya, Takuya Yamamoto, Kenji Tajima, Takuya Isono, Toshifumi Satoh Metallopolymer-block-oligosaccharide for sub10 nm microphase separation, Polymer Chemistry 2020, 17, DOI: 10.1039/d0py00271b.

K. Tajima, K. Tahara, J. Ohba, R. Kusumoto, R. Kose, H. Kono, T. Matsushima, K. Fushimi, T. Isono, T. Yamamoto, T. Satoh Detailed Structural Analyses of Nanofibrillated Bacterial Cellulose and Its Application as Binder Material for a Display Device, Biomacromolecules 2020, 21, 2, 581-588, DOI: 10.1021/acs.biomac.9b0132.

Takojima, K., Saito, T., Vevert, C., Ladelta, V., Bilalis, P., Watanabe, J., Hatanaka, S., Konno, T., Yamamoto, T., Tajima, K., Hadjichristidis, N., Isono, T., Satoh, T. Facile synthesis of poly(trimethylene carbonate) by alkali metal carboxylate-catalyzed ring-opening polymerization, Polymer Journal, 52, 103-110(2020), DOI: 10.1038/s41428-019-0264-6.

Kohei Yoshida, Takuya Yamamoto, Kenji Tajima, Takuya Isono, and Toshifumi Satoh Installing a functional group into the inactive ω-chain end of PMMA and PS-b-PMMA by terminal-selective transesterification, Polym. Chem. 2019, 10, 3390-3398, DOI: 10.1039/C9PY00315K.

Tatsuya Saito, Kaoru Takojima, Takafumi Oyama, Shintaro Hatanaka, Takashi Konno, Takuya Yamamoto, Kenji Tajima, Takuya Isono, and Toshifumi Satoh Trimethyl Glycine as an Environmentally-Benign and Biocompatible Organocatalyst for Ring-Opening Polymerization of Cyclic Carbonate, ACS Sustainable Chem. Eng. 2019, 7, 8868-8875, DOI: 10.1021/acssuschemeng.9b00884.

Takafumi Oyama, Shingo Kobayashi, Tetsuo Okura, Shunsuke Sato, Kenji Tajima, Takuya Isono, and Toshifumi Satoh Biodegradable Compatibilizers for Poly(hydroxyalkanoate)/Poly(ε-caprolactone) Blends through Click Reactions with End-Functionalized Microbial Poly(hydroxyalkanoate)s, ACS Sustainable Chem. Eng. 2019, 7, 8, 7969-7978, DOI: 10.1021/acssuschemeng.9b00897.

Yukari Numata, Hiroyuki Kono, Akane Mori, Ryota Kishimoto, and Kenji Tajima Structural and rheological characterization of bacterial cellulose gels obtained from Gluconacetobacter genus, Food Hydrocolloids, 92, 233-239 DOI: 10.1016/j.foodhyd.2019.01.060.

Takuya Isono, Nao Kawakami, Kodai Watanabe, Kohei Yoshida, Issei Otsuka, Hiroaki Mamiya, Hajime Ito, Takuya Yamamoto, Kenji Tajima, Redouane Borsali, and Toshifumi Satoh Microphase Separation of Carbohydrate-Based Star-Block Copolymers with Sub-10 nm Periodicity, Polymer Chemistry, ASAP, DOI: 10.1039/C8PY01745J.

Kodai Watanabe, Satoshi Katsuhara, Hiroaki Mamiya, Takuya Yamamoto, Kenji Tajima, Takuya Isono, and Toshifumi Satoh Downsizing of Feature in Microphase-Separated Structures via Intramolecular Crosslinking of Block Copolymers, Chemcial Sciences, ASAP, DOI: 10.1039/C8SC05016C.

Highlighted in Synfacts 2019, 15, 492."DOI: 10.1055/s-0037-1612488"

Takuya Yamamoto, Masaaki Hosokawa, Minato Nakamura, Shin-ichiro Sato, Takuya Isono, Kenji Tajima, Toshifumi Satoh, Masamichi Sato, Yasuyuki Tezuka, Akinori Saeki, and Yoshihiro Kikkawa Synthesis, Isolation, and Properties of All Head-to-Tail Cyclic Poly(3-hexylthiophene): Fully Delocalized Exciton over the Defect-Free Ring Polymer, Macromolecules, Article ASAP, DOI: 10.1021/acs.macromol.8b01681..

Kohei Yoshida, Shunma Tanaka, Takuya Yamamoto, Kenji Tajima, Redouane Borsali, Takuya Isono, and Toshifumi Satoh Chain-End Functionalization with a Saccharide for 10 nm Microphase Separation: “Classical” PS‐b‐PMMA versus PS‐b‐PMMA-Saccharide, Macromolecules, 2018, 51 (21), pp 8870–8877, DOI: 10.1021/acs.macromol.8b02069..

Yoshinobu Mato, Kohei Honda, Kenji Tajima, Takuya Yamamoto, Takuya Isono, and Toshifumi Satoh A versatile synthetic strategy for macromolecular cages: intramolecular consecutive cyclization of star-shaped polymers, Chemical Science, ASAP, DOI: 10.1039/C8SC04006K.

Kohei Yoshida, Lin Tian, Ken Miyagi, Akiyoshi Yamazaki, Hiroaki Mamiya, Takuya Yamamoto, Kenji Tajima, Takuya Isono, and Toshifumi Satoh Facile and Efficient Modification of Polystyrene-block-poly(methyl methacrylate) for Achieving Sub-10 nm Feature Size, Macromolecules, 2018, 51 (20), 8064–8072, DOI: 10.1021/acs.macromol.8b01454.

Tomoki Shingu, Takuya Yamamoto, Kenji Tajima, Takuya Isono, and Toshifumi Satoh Synthesis of μ-ABC Tricyclic Miktoarm Star Polymer via Intramolecular Click CyclizationPolymers 2018, 10(8), 877, DOI: 10.3390/polym10080877.

Takuya Isono, Tetsuya Sasamori, Kohei Honda, Yoshinobu Mato, Takuya Yamamoto, Kenji Tajima, and Toshifumi Satoh Multicyclic Polymer Synthesis through Controlled/Living Cyclopolymerization of α,ω-Dinorbornenyl-Functionalized MacromonomersMacromolecules, 2018, 51 (10), pp 3855–3864, DOI: 10.1021/acs.macromol.8b00355.

Tatsuya Saito, Yusuke Aizawa, Takuya Yamamoto, Kenji Tajima, Takuya Isono, and Toshifumi Satoh Alkali Metal Carboxylate as an Effi cient and Simple Catalyst for RingOpening Polymerization of Cyclic Esters, Macromolecules 2018, 51, 3, 689-696, DOI: 10.1021/acs.macromol.7b02566.

Takuya Isono, Brian J. Ree, Kenji Tajima, Redouane Borsali, and Toshifumi Satoh Highly Ordered Cylinder Morphologies with 10 nm Scale Periodicity in Biomass-Based Block Copolymers, Macromolecules, 51 (2), 528-437 (2018), DOI:10.1021/acs.macromol.7b02279.

Nojima S., Fujishima A., Kato K., Ohuchi K., Shimizu N., Yonezawa K., Tajima K., Yao M. Crystal structure of the flexible tandem repeat domain of bacterial cellulose synthesis subunit C, Scientific Reports 7, Article number: 13018 (2017), DOI:10.1038/s41598-017-12530-0.

Tajima, K., Kusumoto, R., Kose, R., Kono, H., Matsushima, T., Isono, T., Yamamoto, T.,Satoh, T. One-step production of amphiphilic nano-fibrillated cellulose using a cellulose-producing bacterium, Biomacromolecules, Ahead of Print (2017), 査読有.

Yukari Numata, Hiroyuki Kono, Minato Tsuji, Kenji Tajima Structural and mechanical characterization of bacterial cellulose-polyethylene glycol diacrylate composite gels, Carbohydr. Polym., 2017, 173, 67-76, DOI: 10.1016/j.carbpol.2017.05.077.

Ryoto Tanaka, Kodai Watanabe, Takuya Yamamoto, Kenji Tajima, Takuya Isono, Toshifumi Satoh A facile strategy for manipulating micellar size and morphology through intramolecular cross-linking of amphiphilic block copolymers, Polym. Chem., 2017,8, 3647-3656, DOI: 10.1039/C7PY00646B.

Yusuke Satoh, Hirohiko Matsuno, Takuya Yamamoto, Kenji Tajima, Takuya Isono, Toshifumi Satoh Synthesis of Well-Defined Three- and Four-Armed Cage-Shaped Polymers via “Topological Conversion” from Trefoil- and Quatrefoil- Shaped Polymers, Macromolecules, 2017, 50, 97-106, DOI: 10.1021/acs.macromol.6b02316.

Watanabe, K., Tanaka, R., Takada, K., Kim, M.-J., Lee, J.-S., Tajima, K., Isono, T., Satoh, T. Intramolecular olefin metathesis as a robust tool to synthesize single-chain nanoparticles in a size-controlled manner , Polym. Chem., 2016,7, 4782-4792, DOI: 10.1039/C6PY00795C.

Kenji Tajima, Xuerong Han, Yoshiki Hashimoto, Yasuharu Satoh, Toshifumi Satoh, and Seiichi Taguchi In vitro synthesis of polyhydroxyalkanoates using thermostable acetyl-CoA synthetase, CoA transferase, and PHA synthase from thermotorelant bacteria, J. Biosci. Bioeng., in press.

H. Kono, K. Oshima, H. Hashimoto, Y. Shimizu, and K. Tajima NMR characterization of sodium carboxymethyl 1 cellulose. 2. Chemical shift 2 assignment and conformation analysis of substituent groups, Carbohydrate Polymer, 2016, 150, 241-249.

Hiroyuki Kono, Kazuhiro Oshima, Hisaho Hashimoto, Yuuichi Shimizu, Kenji Tajima NMR characterization of sodium carboxymethyl cellulose: Substituent distribution and mole fraction of monomers in the polymer chains, Carbohydrate Polymers, 2016, 146, 1-9.

Isono, Takuya; Miyachi, Kana; Satoh, Yusuke; Nakamura, Ryosuke; Zhang, Yao; Otsuka, Issei; Tajima, Kenji; Kakuchi, Toyoji; Borsali, Redouane; Satoh, Toshifumi Self-Assembly of Maltoheptaose-block-Polycaprolactone Copolymers: Carbohydrate-Decorated Nanoparticles with Tunable Morphology and Size in Aqueous Media, Macromolecules, in press.

Satoh, Y., Miyachi, K., Matsuno, H., Isono, T., Tajima, K., Kakuchi, T.,Satoh, T. Synthesis of Well-Defined Amphiphilic Star-Block and Miktoarm Star Copolyethers via t-Bu-P4-Catalyzed Ring-Opening Polymerization of Glycidyl Ethers, Macromolecules (Washington, DC, U. S.), 49 (2), 499-509 (2016).

Tajima, K., Iwamoto, K., Satoh, Y., Sakai, R., Satoh, T.,Dairi, T. Advanced functionalization of polyhydroxyalkanoate via the UV-initiated thiol-ene click reaction, Appl. Microbiol. Biotechnol., 2016, 100, 4375-4383..

Y., Numata; S., Masaki; K., Tajima, Mechanical Properties of a Bacterial Cellulose/Polyethylene Glycol Gel with a Peripheral Region Cross-Linked by Polyethylene Glycol Diacrylate, Polym. J., 2015, 48, 317-321..

Ju, Fang; Shin, Kawano; Kenji, Tajima; Tetsuo, Kondo, In Vivo Curdlan/Cellulose Bionanocomposite Synthesis by Genetically Modified Gluconacetobacter xylinus, Biomacromolecules, 2015, 16, 3154?3160.

Tatsuya, Saito; Yusuke, Aizawa; Kenji, Tajima; Takuya, Isono; Toshifumi, Satoh, Organophosphate-catalyzed bulk ring-opening polymerization as an environmentally benign route leading to block copolyesters, end-functionalized polyesters, and polyester-based polyurethane, Polym. Chem., 2015, 6, 4374-4384.

Isono, T., Asai, S., Satoh, Y., Takaoka, T., Tajima, K., Kakuchi, T., Satoh, T., Controlled/Living Ring-Opening Polymerization of Glycidylamine Derivatives Using t-Bu-P4/Alcohol Initiating System Leading to Polyethers with Pendant Primary, Secondary, and Tertiary Amino Groups, Macromolecules, 48 (10), 3217-3229 (2015).

Yukari, Numataa; Tadanori, Sakata; Hidemitsu, Furukawa; Kenji, Tajima; Bacterial cellulose gels with high mechanical strength, Mater. Sci. Eng. C 2015, 47, 57?62.

Isono, T., Kondo, Y., Ozawa, S., Chen, Y., Sakai, R., Sato, S.-i., Tajima, K., Kakuchi, T., Satoh, T., Stereoblock-like Brush Copolymers Consisting of Poly(L-lactide) and Poly(D-lactide) Side Chains along Poly(norbornene) Backbone: Synthesis, Stereocomplex Formation, and Structure-Property Relationship, Macromolecules, 47 (20), 7118-7128 (2014).

Inoue, K. Takadono, R. Nishiyama, K. Tajima, T. Kobayashi, T. Ojima, Characterization of an Alginate Lyase, FlAlyA, from Flavobacterium sp. Strain UMI-01 and Its Expression in Escherichia coli., Mar. Drugs 12, 4693-4712 (2014).

X. Han, Y. Satoh. Y. Kuriki, T. Seino, S. Fujita, T. Suda, T. Kobayashi, and K. Tajima*, Polyhydroxyalkanoate production by using a novel bacterium Massilia sp. UMI-21 isolated from seaweed, and molecular cloning of its polyhydroxyalkanoate synthase gene, J. Biosci. Bioeng. 118, 514-519 (2014).

T. Isono, Y. Satoh, K. Miyachi, Y. Chen, S.-i. Sato, K. Tajima, T. Satoh, and T. Kakuchi, Synthesis of Linear, Cyclic, Figure-Eight-Shaped, and Tadpole-Shaped Amphiphilic Block Copolyethers via t-Bu-P4-Catalyzed Ring-Opening Polymerization of Hydrophilic and Hydrophobic Glycidyl Ethers, Macromolecules 47 (9), 2853-2863 (2014).

Ryota Kose, Naoki Sunagawa, Makoto Yoshida, Kenji Tajima, One-step production of nanofibrillated bacterial cellulose (NFBC) from waste glycerol using Gluconacetobacter intermedius NEDO-01, Cellulose, 20, 2971-2979 (2013).

Takaaki Fujiwara, Keisuke Komoda, Naofumi Sakurai, Kenji Tajima, Isao Tanaka, Min Yao, The c-di-GMP recognition mechanism of the PilZ domain of bacterial cellulose synthase subunit A, Biochem. Biophys. Res. Commun., 431, 802-807 (2013).

Naoki Sunagawa, Takaaki Fujiwara, Takanori Yoda, Shin Kawano, Yasuharu Satoh, Min Yao, Kenji Tajima, and Tohru Dairi, Cellulose complementing factor (Ccp) is a new member of the cellulose synthase complex (terminal complex) in Acetobacter xylinum, J. Biosci. Bioeng., 115(6), 607-612 (2013).